For an introduction to our lab's research interests, please see these recent reviews/perspectives:
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Cell type-specific enrichment of somatic aneuploidy in the mammalian brain
Eran A. Mukamel, Hanqing Liu, M. Margarita Behrens, Joseph R. Ecker
BioRxiv https://doi.org/10.1101/2023.12.18.572285Cell type-specific effects of age and sex on human cortical neurons
Jo-Fan Chien, Hanqing Liu, Bang-An Wang, Chongyuan Luo, Anna Bartlett, Rosa Castanon, Nicholas D. Johnson, Joseph R. Nery, Julia Osteen, Junhao Li, Jordan Altshul, Mia Kenworthy, Cynthia Valadon, Michelle Liem, Naomi Claffey, Caz O'Connor, Luise A Seeker, Joseph R. Ecker, M. Margarita Behrens, Eran A. Mukamel
BioRxiv https://doi.org/10.1101/2023.11.11.566717Divergent single cell transcriptome and epigenome alterations in ALS and FTD patients with C9orf72 mutation
Junhao Li, Manoj K Jaiswal, Jo-Fan Chien, Alexey Kozlenkov, Jinyoung Jung, Ping Zhou, Mahammad Gardashli, Luc J. Pregent, Erica Engelberg-Cook, Dennis W. Dickson, Veronique V. Belzil, Eran A Mukamel, Stella Dracheva
Nature Communications 14, Article number: 5714Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes
Fangming Xie, Ethan J. Armand, Zizhen Yao, Hanqing Liu, Anna Bartlett, M. Margarita Behrens, Yang Eric Li, Jacinta D. Lucero, Chongyuan Luo, Joseph R. Nery, Antonio Pinto-Duarte, Olivier Poirion, Sebastian Preissl, Angeline C. Rivkin, Bosiljka Tasic, Hongkui Zeng, Bing Ren, Joseph R. Ecker, Eran A. Mukamel
Cell Genomics 3, 100342 (2023) https://doi.org/10.1016/j.xgen.2023.100342 (open access)