Single Cell Methylomes Identify Neuronal Subtypes and Regulatory Elements in Mammalian Cortex

Science 357, 600 (2017)

Chongyuan Luo1,2,†, Christopher L. Keown3,†, Laurie Kurihara4, Jingtian Zhou1,5, Yupeng He1,5, Junhao Li3, Rosa Castanon1, Jacinta Lucero6, Joseph R. Nery1, Justin Sandoval1, Brian Bui6, Terrence J. Sejnowski2,6, Timothy Harkins4, Eran A. Mukamel3,*, M. Margarita Behrens6,*, Joseph R. Ecker1,2,*

  1. Genomic Analysis Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, United States.
  2. Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, United States.
  3. Department of Cognitive Science, University of California, San Diego, La Jolla, CA 92037, United States.
  4. Swift Biosciences Inc, 58 Parkland Plaza, Ste. 100, Ann Arbor, MI 48103, United States.
  5. Bioinformatics Program, University of California, San Diego, La Jolla, CA 92093, United States.
  6. Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, United States.

Contact: emukamel [at] ucsd [dot] edu; mbehrens [at] salk [dot] edu; ecker [at] salk [dot] edu


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Mouse and human brain cell types defined by DNA methylation: tSNE browser

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